Stimulation and sedation biphasic alcohol effects scale and 12 subjective intoxication were measured multiple times after drinking. Assessing the stimulant and sedative effects of alcohol. Assessed multiple times, starting at 50 minutes after priming drink until 230 minutes after priming drink. The effect of alcohol on a person will vary according to the persons mood, the time of day, amount of food in the stomach, the mixer used, how fast the person drinks, and what and why they are drinking. Usually at the beginning of the consumption, while the level of alcohol in blood is increasing, it is generally perceived as a stimulant and when decreasing as a sedative. In this study, we examined the caeq in a student sample n 932 and in a clinical sample of alcohol dependent inpatients n 744. The biphasic alcohol effects scale baes martin et al. It is sensitive to the stimulant and sedative effects of alcohol observed during the ascending and descending limbs of the blood alcohol curve. In this study, we examined the caeq in a student sample n 932 and in a clinical sample of alcoholdependent inpatients n 744. Validation of the brief biphasic alcohol effects scale b. Self report measures addiction research center uwmadison. The comprehensive alcohol expectancy questionnaire caeq.
The biphasic alcohol effects scale baes is a reliable and valid 14item measure of alcohol s acute stimulant and sedative effects, but its length may preclude use in research paradigms with time. Alcohol affects multiple neurotransmitter systems in the brain and brain functions. Pdf development and validation of the biphasic alcohol. Alcohol produces stimulant and sedative effects, and both types of effect are thought to influence drinking practices.
Biphasic alcohol effects scale baes addiction research center. Alcohol use has complex effects on cardiovascular cv health. In previous studies, various tools were used to assess these effects, including expectancy questionnaires. Biobehavioral effects of baclofen in anxious alcohol. This measure is a commonly used 14item scale that assesses stimulant 7 items and sedative 7 items subjective effects of drugs on a 10point likert scale. Measuring the shortterm biphasic effects of alcohol christopher s. The biphasic alcohol effects scale baes was developed to measure subjective ratings of alcohol sedation and stimulation, and the baes shows a pattern of stimulant effects on the ascending limb of the breath alcohol concentration brac curve and sedative effects on the descending limb of the brac curve with moderate doses of alcohol. A subjective assessment of the shortterm effects of alcohol. Published reports of its effects on adolescent drinking, however, are limited to. Development and validation of the biphasic alcohol effects.
We investigated specific subjective effects of naltrexone pretreatment or placebo during various intervals on the breath alcohol level bal curve in nonalcoholic volunteers. The biphasic alcohol effects scale baes is a reliable and valid 14item measure of alcohols acute stimulant and sedative effects, but its. Sensitivity to these effects may increase the risk for the development of alcoholism. Biphasic effects of alcohol as a function of circadian phase. Individual differences in the biphasic effects of ethanol. Effects of acute alcohol consumption on emotion recognition in social alcohol drinkers jasmine n khouja1,2 3, angela s attwood1,2 3. The 14item biphasic alcohol effects scale baes was selected because it is one of the most widely used subjective alcohol assessment tools in studies involving actual administration of alcohol. The fivefactor structure was confirmed by means of confirmatory factor analysis. Confirming the factor structure of the anticipated biphasic alcohol effects scale. Only one existing ae measure, the anticipated biphasic alcohol effects scale abaes. The biphasic alcohol effects scale baes is widely used to assess stimulant and sedative alcohol effects.
The time points for all subjective measures were adopted from the original study. Alcohol challenge responses predict future alcohol use disorder. Fifteen highrisk social drinkers with an alcoholic father and 14 lowrisk no alcoholic relatives in at least two generations subjects were tested in a doubleblind, placebocontrolled study of the effects of 50 mg. Ghrelin is supressed by intravenous alcohol and is related. Biphasic stimulant and sedative effects of ethanol. Rewarding, stimulant, and sedative alcohol responses and. Mar 11, 2009 the utility of one of the most widely used subjective alcohol assessment tools, the biphasic alcohol effects scale baes has been somewhat limited based on lack of psychometric studies in large and diverse samples, a range of alcohol doses, the length of the measure, and the original instructional set which precluded baseline measurement and disclosed to subjects that they received alcohol. The visual analogue scale vas consisted of descriptive words rated on a scale of 07. Seven items ranging from 0 not at all to extremely 10 with higher measurements indicating higher stimulation. Naltrexone and memantine effects on alcohol drinking. Effects of naltrexone on alcohol sensitivity and genetic. The biphasic alcohol effects scale baes is a reliable and valid 14. Inasmuch as naltrexone affects drinking by altering the subjective responses to alcohol, adolescents unique patterns of alcohol sensitivity may in.
This article describes the development and preliminary validation of the biphasic alcohol effects scale baes, a self. The utility of one of the most widely used subjective alcohol assessment tools, the biphasic alcohol effects scale baes has been somewhat limited based on lack of psychometric studies in large and diverse samples, a range of alcohol doses, the length of the measure, and the original instructional set which precluded baseline measurement and disclosed to subjects that they received. Expanding the utility of the biphasic alcohol effects scale. Gabra2 alleles moderate the subjective effects of alcohol.
Alcohol induced changes in stimulation and sedation are commonly assessed with selfreport questionnaires in human research and with physical activity monitoring in animal research. Addiction research center inventory, adjective checklist, alcohol, amphetamine, arci, baes, benzedrine, biphasic alcohol effects scale, buzz, cigarettes, dizziness, deq, drug effects. The associations between drinking and cv diseases such as hypertension, coronary heart disease, stroke, peripheral arterial disease, and cardiomyopathy have been studied extensively. The biphasic alcohol effects scale baes was developed to measure subjective ratings of alcohol sedation and stimu lation, and the baes shows a pattern of. Validation of the brief biphasic alcohol effects scale bbaes. Alcohol sensitivity questionnaire 1 2 5 kimberly a. A biphasic drug is one that has different effects on the body at different blood concentration levels. Effect of memantine on cueinduced alcohol craving in. Alcohol and other drug aod involvement by adolescents is still a major public health issue in this country. The biphasic alcohol effects scale baes is a reliable and valid 14item measure of alcohols acute stimulant and sedative effects, but its length may preclude use in research paradigms with time.
The subjective effects of alcohol scale semantic scholar. Main outcome measures the biphasic alcohol effects scale, the alcohol urge questionnaire, the profile of mood states, and the alcohol rating scale were administered. The biphasic alcohol effects scale 9 includes seven items that assess stimulant effects and seven that assess sedative effects. Results of exploratory factor analyses supported a 3factor model which captured the. An abbreviated scale bbaes and a comprehensive measures of alcohol effects seas demonstrate. Hierarchical linear models showed that the asq reliably predicted each of these outcomes following alcohol but not. Effect of naltrexone on subjective alcohol response in. Request pdf validation of the brief biphasic alcohol effects scale bbaes the biphasic alcohol effects scale baes is a reliable and valid 14item. Difference of the naltrexones effects in social drinkers.
Updated 7152019 4ps plus tspeq 12step participation expectancies questionnaire aos abstinence orientation scale arme armesf abstinencerelated motivational engagement abstinencerelated motivational engagement short form accod accooccurring disorder screen aaqsa acceptance and action questionnaire substance abuse aaii acceptance of an alcoholic identity instrument ahimsa. Jan 26, 2012 brief biphasic alcohol effects scale stimulation subscale baes. Effects of naltrexone on adolescent alcohol cue reactivity. Assessment scale, biphasic alcohol effect scale, and the short version of the pro. Although the abaes provides an important theoretical contribution to the literature, the effects assessed by the.
In the present study, 100 college students, who were either coas n18 or conas n82, completed the biphasic alcohol effects scale a selfreport measure of stimulation and sedation. Results individuals with at least 1 copy of the g allele reported lower alcohol craving and higher alcoholinduced high across rising breath alcohol concentrations. Studies of acute alcohol challenge have revealed the neural and behavioral impairments that accompany intoxication. Biphasic drugs are to be confused with biphasic drugrelease, a common method of pharmaceutical drug administration in which a drug is coated with film, creating one layer that absorbs immediately, and one that releases over time. The secondary protocols can then be used to obtain detailed information on a specific substance. Alcoholinduced changes in stimulation and sedation are commonly assessed with selfreport questionnaires in human research and with physical activity monitoring in animal research. The aim of the study was to prepare the polish adaptation of the scale in order to determine its reliability and offer a preliminary assessment of validity. Areas covered include the effects of alcohol on body parts, the health effects of acute alcohol use, the health conditions related to chronic alcohol use, and the effects of alcohol on other people and populations. Visual analogue scales 0100 mm were used to assess similarity to ethanol, euphoria, and alcohol craving 10. The analog scale of responses ranges from not at all to extremely.
Alcohol produces biphasic effects of both stimulation and sedation. This definition is appropriate given that most assessment measures are validated and standardized on teenagers in this age range. Intensity of alcohol effects was assessed with the number of drinks. Expanding the utility of the biphasic alcohol effects scale baes. The biphasic alcohol effects scale baes is a selfreport, unipolar adjective rating scale that is designed to measure both stimulant and sedative effects of.
Anticipated biphasic effects of alcohol vary with risk for alcoholism. Alcohol consumption is characterized by biphasic stimulant and sedative effects. Martin et al, 1993 is a 14item unipolar adjective rating scale designed to measure both the stimulant and sedative effects of alcohol. Auq and subjective responses to alcohol via the biphasic alcohol effects scale baes 29 and a modified version of the drug effects questionnaire. The modified polish adaptation of baes is now complete as skala efektow picia alkoholu sepa scale of alcohol drinking effects. Bwsq1 bwsq2 benzodiazepine withdrawal symptom questionnaire biq bicultural involvement questionnaire baes abaes bbaes biphasic alcohol effects scale anticipated biphasic alcohol effects scale brief biphasic alcohol effects scale bbvtraq bloodborne virus transmission risk. Effects of acute alcohol consumption on the human brain. As stated previously, the biphasic alcohol effects scale baes. Expanding the utility of the biphasic alcohol effects. The items are presented in alphabetical order, and are rated on an 11point rating scale from 0not at. Development and validation of the biphasic alcohol effects scale.
A subjective assessment of the shortterm effects of. Brief biphasic alcohol effects scalestimulation subscale baes. A rating scale approach was chosen as the response format because it is easily understood by most participants and can be completed quickly, which was important given that the seas was designed to be administered multiple times. A rating scale approach was chosen as the response format because it is easily understood by most participants. Subjective responses to alcohol were measured using the biphasic alcohol effects scale baes 15 at approximately 30 minutes before drinking and again at 25 and 55 minutes after the initiation of alcohol consumption. Alcohol dependence scale ads alcohol expectancy inventory aei alcohol hangover questionnaire ahq alcohol sensitivity questionnaire asq alcohol use history auh short michigan alcohol screening tests smast michigan assessment screening test for alcohol and drugs mastad biphasic alcohol effects scale baes cage. Until recently, the effect of alcohol on neural mechanisms has. Combined effects of alcohol and caffeine full text view. Jan 01, 20 the biphasic alcohol effects scale baes was developed to measure subjective ratings of alcohol sedation and stimulation, and the baes shows a pattern of stimulant effects on the ascending limb of the breath alcohol concentration brac curve and sedative effects on the descending limb of the brac curve with moderate doses of alcohol. The comprehensive alcohol expectancy questionnaire. Acute biphasic alcohol effects scale baes, visual analogue scale for craving vasc, blood alcohol concentration bac and food preference scale were measured in 26 men.
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