Palmoplantar keratoderma definition keratoderma is actually a term that literally means a marked skin thickening. Palmoplantar keratoderma top 25 questions palmoplantar. Help others answering the top 25 questions of palmoplantar keratoderma. In recalcitrant or severe cases, the use of pharmacological treatments, such as keratolytics or acitretin, may be required. Palmoplantar keratoderma ppk constitutes a heterogeneous group of disorders characterized by thickening of the palms and the soles of individuals who are affected.
Acitretin 20 mgday was prescribed with mild improvement, but therapy was stopped because of metabolic side effects. Schopfschulzpassarage syndrome is a rare ectodermal dysplasia characterized by hypodontia, hypotrichosis, nail dystrophy, palmoplantar keratoderma, and periocular and eyelid margin hidrocystomas. Aquagenic palmoplantar keratoderma apk is a rare, acquired condition that presents as papules on the palms, and rarely the soles, upon immersion in water. Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the palms and soles autosomal recessive and dominant, xlinked, and acquired forms have all been described. These forms of ppk may be present in more than one family member. Palmoplantar keratoderma with deafness is a disorder characterized by skin abnormalities and hearing loss. The thickening may be symmetrical and found in infants during their first few months of life. Palmoplantar keratodermas are a group of disorders characterized by thickening of the skin on the palms of the hands and soles of the feet of affected individuals. Acquired palmoplantar keratoderma shaily patel,1 matthew zirwas2 and joseph c. Kertatoderma can be inherited, acquired, and rarely, paraneoplastic ie secondary to an internal malignancy. Acquired palmoplantar keratoderma associated with hypothyroidism. It is characterized by thickening of the palms and the soles of individuals who are affected.
It may occur as part of a generalised skin condition some of which may be inherited or as a result of another illness. Acquired forms of punctate ppkd may be associated with lynch type ii malignancies, chronic arsenicosis, angiosarcoma of liver, bronchial adenocarcinoma. Aquagenic palmoplantar keratoderma is an acquired condition characterized by burning and edema limited to the hands after brief immersion in water. A palmoplantar keratoderma is defined as a persistent thickening of the epidermis of palms. Epidermolytic palmoplantar keratoderma vorner type case report. Multiple palmoplantar eccrine syringofibroadenomas have. The topic acquired palmoplantar keratoderma you are seeking is a synonym, or alternative name, or is closely related to the medical condition acquired keratoderma. In the acquired forms the cure seems to have been permanent. Palmoplantar keratoderma genetic and rare diseases. Palmoplantar keratoderma is a thickening of the soles of feet and the palms of the hands. Palmoplantar keratoderma ppk can be either acquired during the lifetime more commonly or inherited. Patients with genetic pal moplantar keratoderma remain. The family of palmoplantar keratodermas are relatively uncommon diseases. Home types of ichthyosis palmoplantar keratoderma ppk what is palmoplantar keratoderma.
Pdf palmoplantar keratodermas ppks are a diverse entity of disorders that are characterized by abnormal thickening of the skin on the. Acquired palmoplantar keratoderma is more likely to present in adulthood compared with inherited keratodermas which usually present in childhood. The 3 patients described possess a striking similarity to those with transient reactive papulotranslucent acrokeratoderma. It may also appear as a snakeskin or have a waxy appearance in infants. They can also be acquired, such as manifestations of several diseases table. Keratoderma climactericum is a type of acquired palmoplantar keratoderma. Palmoplantar keratodermas, also called keratosis palmaris et plantaris or ppks, are a heterogeneous group of disorders marked by an unusual thickening of the. Palmoplantar keratoderma ppk is a common hereditary cutaneous disorder characterized by marked hyperkeratosis on the surface of palms and soles hennies et al. The condition may be subdivided into hereditary keratodermas, acquired forms, and conditions in which ppk is an associated feature of a specific dermatosis. Ppk can be characterized as either inherited or acquired. Palmoplantar keratosis or palmoplantar keratoderma ppk constitutes a heterogeneous group of disorders characterized by excessive epidermal thickening of the palms and soles of affected individuals 1.
G\lu\nther,md, dsc, glasgow, scotland nine patients with palmoplantar kera toderma were treated with vitamin a acid retinoic acid 0. Additionally, the symptoms of punctate palmoplantar keratoderma type i and some of the treatments for the condition may have side effects that impact a persons quality of life. Keratoderma is a term that means marked thickening of the skin. Pdf acquired palmoplantar keratoderma shaily patel.
Palmoplantar means palms of the hands and soles of the feet, and keratoderma means thickened skin. Vitamin a acid in the clinical investigations and experimental results with patients seigwart h. Acquired palmoplantar keratoderma pdf palmoplantar keratodermas ppks are a diverse entity of disorders that are characterized by abnormal thickening of the skin on the palms and soles. Classification of keratodermas depends on whether or not it is inherited. The full text of this article hosted at is unavailable due to technical difficulties. Acquired palmoplantar keratoderma may also be due to many causes. Successful treatment of acquired palmoplantar keratodermas.
Focal palmoplantar keratoderma inassociation with carcinoma of the esophagus. Differentiation between acquired and hereditary forms is essential for adequate treatment and patient counseling. In regard to successful corrective therapy treatmentelimination of the cause of acquired ppk, as well as for genetic counseling for pregnant women and patients wishing to conceive, it is important to distinguish hereditary ppk from acquired disease. Acquired palmoplantar keratoderma pdf palmoplantar keratodermas ppks are a diverse entity of disorders that are characterized by abnormal thickening of. Palmoplantar refers to the skin on the soles of the feet and palms of the hands. English iii1 1 department of dermatology, university of. Related information on causes of palmoplantar keratoderma. Ppk has been classified into diffuse, focal, and punctate forms according to the pattern of hyperkeratosis on the palms and soles lucker et al. Palmoplantar keratoderma ppk or keratosis palmaris et plantaris is part of a group of disorders of the skin affecting primarily the palms of the hands and soles of the feet. Palmoplantar keratodermas ppks are a diverse entity of disorders that are characterized by abnormal thickening of the skin on the palms and soles. There have been some reports of internal malignancy associated with nonfamilial palmoplantar keratoderma of late onset, 14 as well as of esophageal squamous cell carcinoma in association with familial keratosis palmaris et plantaris of early onset. Diffuse ppk develops at birth or shortly thereafter and involves the entire.
Acquired palmoplantar keratoderma that may be caused by infections, medications and drugs, or various skin disorders. Affected individuals develop unusually thick skin on the palms of the hands and soles of the feet palmoplantar keratoderma beginning in childhood. The main types of palmoplantar keratoderma are shown below. Paraneoplastic palmoplantar keratoderma ppk is an acquired dermatosis that presents with hyperkeratosis of the palms and soles in association with visceral malignancies eg, esophageal, gastric, pulmonary, and urinarybladder carcinomas. Current concepts in diagnosing and treating keratoderma.
Palmoplantar keratoderma is classified based on whether it. Natural cure for palmoplantar keratoderma and alternative. How to diagnose and manage hereditary palmoplantar. Palmoplantar keratoderma ppk constitutes a heterogeneous group of disorders. Punctate palmoplantar keratoderma type i does not affect a persons lifespan. Sporadic or acquired forms of ppks and genetic or hereditary forms exist. Palmoplantar keratodermas ppk may be categorized as acquired or hereditary. In rare forms of ppk, organs other than the skin may also be affected. Palmoplantar keratodermas ppks consist of a heterogeneous group of disorders characterized by thickening of the palms and soles. In recent years, speculation has arisen that a molecular genetic classification system will replace the traditional, clinically based, descriptive systems. Tr eatment of palmoplantar keratoderma with continuous. Palmoplantar keratoderma description, causes and risk factors. An adverse reaction to influenza vaccination, australasian journal of dermatology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Our database lists the following as having palmoplantar keratoderma as a symptom of that condition. Palmoplantar keratoderma an overview sciencedirect topics. Pdf acquired palmoplantar keratoderma researchgate. Transgredient ppk extends beyond palmoplantar skin, contiguously or as callosities on. Ppk can also be a feature of various underlying syndromes. Traditionally they have been classified as either hereditary or acquired and are distinguished from each other on the basis of mode of inheritance, presence of transgrediens defined as contiguous extension of hyperkeratosis beyond the palmar and. Some congenital keratodermas have one or more associated disorders involving bone, muscle, hair, nails, teeth, skin colour, nervous system and the eyes. Acquired palmoplantar keratoderma while palmoplantar keratoderma is in most cases a genetic condition, there are situations in which it can be acquired, usually as a symptom of some inflammatory skin condition, such as psoriasis, eczema, ichthyosis, scabies, or dermatitis. So palmoplantar keratoderma is a disorder in which the skin of the palms and soles is abnormally thick. Palmoplantar keratoderma ppk is a heterogeneous entity of both genetics and acquired keratinization disorder, which is characterized by persistent marked epidermal thickening of palms and soles. Palmoplantar keratoderma medigoo health medical tests. Palmoplantar keratoderma with deafness genetics home.
Palmoplantar keratoderma ppk is a group of skin conditions characterized by thickening of the skin on the palms of the hands and soles of the feet. People with experience in palmoplantar keratoderma help solve this question. Palmoplantar keratodermas ppk comprise a heterogeneous group of keratinization disorders with hyperkeratotic thickening of palms and soles. On the other hand, palmoplantar refers to the skin located on the soles of the feet as well as the palms of the hands. The various forms of ppk can be divided into hereditary forms with only skin problems, hereditary syndromes. Palmoplantar keratoderma is a term used to define a marked thickening of the skin on the palms and soles, either as a focal entity, or diffuse. Many people with this condition do find that they develop more skin lesions with age.
Acquired keratoderma is a keratoderma that is not inherited as a primary genetic condition. This chapter provides a practical overview of keratoderma, and is set out as below. Punctate palmoplantar keratoderma type i genetic and. Congenital palmoplantar keratoderma, which is caused by genetic abnormalities that may be inherited in an autosomal dominant or recessive manner. Palmoplantar keratoderma definition of palmoplantar. Ppk can be either acquired during the lifetime more commonly or inherited. Palmoplantar keratoderma is the name given to a group of conditions where there is abnormal thickening of the skin on the palms of the hands and soles of the feet. Punctate palmoplantar keratodermas remedy publications llc. Acquired ppk may arise due to changes in a persons health or environment. It presents with thickening of the skin of the palms andor soles which may be diffuse involving most of the palms and soles or focal localised mainly to pressure areas. Palmoplantar keratodermas foundation for ichthyosis. Conditions listing palmoplantar keratoderma as a symptom may also be potential underlying causes of palmoplantar keratoderma. Inherited forms of ppk are caused by genetic mutations that result in abnormalities of keratin a skin protein.
Palmoplantar keratoderma is also sometimes known as keratosis palmaris et plantaris. Paraneoplastic palmoplantar keratoderma secondary to. Acquired diffuse keratoderma of the palms and soles with. Palmoplantar keratoderma secondary to uterine cancer is rare. He was treated with keratolytic creams with mild and transient results. Afro caribbeans with atopic diathesis, sometimes exhibit a distinct varietyacquired punctate keratoderma of the palmar creases. Palmoplantar keratodermas ppks are a diverse entity of disorders that are characterized by abnormal thickening of the skin on the palms and. Oral retinoid a vitamin a derivative and topical application of petrolatum salicylate or moisturizer are the main treatments. Acquired keratoderma is a benign skin condition, wherein there is thickening of skin keratoderma of the palms andor soles. Acquired palmoplantar keratodermas are a group of hyperkeratosis disorders with diverse presentation.
Diagnosis and treatment of the underlying aetiology is the most successful course of action. Gudelines on management of palmoplantar keratoderma. Top 25 questions of palmoplantar keratoderma discover the top 25 questions that someone asks himselfherself when is diagnosed with palmoplantar keratoderma palmoplantar keratoderma forum. Pdf athome chiropody as an alternativecomplementary. Is palmoplantar keratoderma transmitted from person to person. Palmoplantar keratoderma ppk ichthyosis support group.
1511 1206 1487 1036 1405 1051 1451 1033 1110 316 191 1488 1124 730 1400 677 192 818 965 336 733 404 1051 938 1386 898 748 983 259 812 848 1419 341 10 183